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Nolan D, Mallal S. Review of the Third International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, Athens 2001. Nutrition and Metabolic Disorders in HIV Infection 3000;1(4):35-53.
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Nolan D, James I, Mallal S. HIV/AIDS. HIV: experiencing the pressures of modern life. Science 2005;307(5714):1422-1424.
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Nolan D, Reiss P, Mallal S. Adverse effects of antiretroviral therapy for HIV infection: a review of selected topics. Expert Opinion on Drug Safety 2005;4(2):201-218.
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John M, Mallal S. CTL responses to HIV and SIV: wrestling with smoke. Nature Immunology 2005;6(3):232-234.
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Gaudieri S, Nolan D, McKinnon E, Witt CS, Mallal S, Christiansen FT. Associations between KIR epitope combinations expressed by HLA-B/-C haplotypes found in an HIV-1 infected study population may influence NK mediated immune responses. Mol. Immunology 2005;42(4):557-560.
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Martin AM, Nolan D, Gaudieri S, Phillips E, Mallal S. Pharmacogenetics of antiretroviral therapy: genetic variation of response and toxicity. Pharmacogenomics 2004;5(6):643-655.
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Nolan D, Gaudieri S, John M, Mallal S. Impact of host genetics on HIV disease progression and treatment: new conflicts on an ancient battleground. Editorial review. AIDS 2004;18(9):1231-1240.
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Nolan D, Mallal S. The role of nucleoside analogues in fat redistribution syndrome. Journal of HIV Therapy 2004;9(2):34-40.
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Nolan D, Mallal S. Thymidine analogue-sparing highly active antiretroviral therapy (HAART). Journal of HIV Therapy 2003;8(1):2-6.
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Nolan D. Metabolic complications associated with HIV protease inhibitor therapy. Drugs 2003 2003;63(23):2555-2574.
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Nolan D, Gaudieri S, Mallal S. Pharmacogenetics: a practical role in predicting antiretroviral drug toxicity?. Journal of HIV Therapy 2003;8(2):36-41.
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Nolan D, Christiansen F. Review of the Fourth International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, San Diego, California. Expert Opinion on Drug Safety 2003;2(1):95-101.
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John M, Mallal S. Hyperlactatemia syndrome in people with HIV infection. Current Opinion in Infectious Diseases 2002;15(1):23-29.
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Nolan D, John M, Mallal S. Antiretroviral therapy and the lipodystrophy syndrome. Part 2: Concepts in aetiopathogenesis. Antiviral Therapy 2001;6(3):145-160.
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Nolan D, Mallal S. Getting to the HAART of Insulin Resistance (Editorial Review). AIDS 2001;15(15):2037-2041.
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John M, Nolan D, Mallal, SA. Antiretroviral therapy and the lipodystrophy syndrome (review). Antiviral Therapy 2001;6(1):9-20.
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Recent Peer Reviewed Articles
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Gaudieri S, Rauch A, Park LP, Freitas E, Herrmann S, Jeffrey G, Cheng W, Pfafferott K, Naidoo K, Chapman R, Battegay M, Weber R, Telenti A, Furrer H, James I, Lucas M, Mallal SA. Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection. J Virol 2006;80(22):11094-11104.
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Pace C, Keller J, Nolan D, James I, Gaudieri S, Moore C, Mallal S. Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation. J Virol 2006;80(18):9259-9269.
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Feeney ME, Tang Y, Pfafferott K, Roosevelt KA, Draenert R, Trocha A, Yu XG, Verrill C, Moore C, Mallal S, Burchett S, McIntosh K, Pelton SI, St. John MA, Hazra R, Klenerman P, Altfeld M, Walker BD, Goulder PRJ. HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response. J Immunology 2005;174(12):7524-7530.
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Phillips EJ, Wong GA, Kaul R, Shahabi K, Nolan DA, Knowles SR, Martin AM, Mallal SA, Shear NH. Clinical and immunogenetic correlates of abacavir hypersensitivity. AIDS 2005;19(9):979-981.
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Martin AM, Nolan D, Mallal S. HLA-B*5701 typing by sequence-specific amplification: validation and comparison with sequence-based typing. Tissue Antigens 2005;65(6):571-574.
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Gillett MJ, Cameron PU, Nguyen HV, Hurley DM, Mallal SA. Iatrogenic Cushing's syndrome in an HIV-infected patient treated with ritonavir and inhaled fluticasone. AIDS 2005;19(07):740-741.
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Leslie A, Kavanagh D, Honeyborne I, Pfafferott K, Edwards C, Pillay T, Hilton L, Thobakgale C, Ramduth D, Draenert R, Le Gall S, Luzzi G, Edwards A, Brander C, Sewell AK, Moore S, Mullins J, Moore C, Mallal S, Bhardwaj N, Yusim K, Phillips R, Klenerman P, Korber B, Kiepiela P, Walker B, Goulder P. Transmission and accumulation of CTL escape variants drives negative associations between HIV polymorphisms and HLA . J Exp Med 2005;201(6):891-902.
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Nolan D. Face to face with lipoatrophy. An interview with David Nolan by Nelson Vergel. GMHC Treatment Issues 2005;19(3-4):1-6.
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Martin A, Nolan D, James I, Cameron P, Keller J, Moore C, Phillips E, Christiansen F, Mallal S. Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4+ T cell counts. AIDS 2005;19(1):97-99.
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Gaudieri S, DeSantis D, McKinnon E, Moore C, Nolan D, Witt C, Mallal S, Christiansen F. Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression. Genes and Immunity 2005;In press:.
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Suter R, McKinnon E, Perkins N, Besier R. The effective life of ivermectin on Western Australian sheep farms - a survival analysis. Preventative Veterinary Medicine 2005;In press:.
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Redgrave BE, Stone SF, French MAH, Krueger R, James I, Price P. The effect of combination antiretroviral therapy on CD5+ B-cells, B-cell activation and hypergammaglobulinemia in HIV-1 patients. HIV Medicine 2005 2005;In press:.
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G Wong, R Kaul, K Shahabi, D Nolan, S Mallal, S Knowles, A Martin, N Shear, E Phillips . Abacavir Hypersensitivity Syndrome: Results of clinical, immunologic and genetic screening. AIDS 2005;:.
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John M, Moore CB, James IR, Mallal SA. Interactive selective pressures of HLA-restricted immune responses and antiretroviral drugs on HIV-1. Antiviral Therapy 2005;10(4):551-555.
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Kiepiela P, Leslie AJ, Honeyborne I, Ramduth D, Thobakgale C, Chetty S, Rathnavalu P, Moore C, Pfafferott KJ, Hilton L, Zimbwa P, Moore S, Allen T, Brander C, Addo MM, Altfeld M, James I, Mallal S, Bunce M, Barber LD, Szinger J, Day C, Klenerman P, Mullins J, Korber B, Walker BD, Goulder PJR. Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. Nature 2004;432:769-775.
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Nolan D, Mallal S. Complications associated with NRTI therapy: update on clinical features and possible pathogenic mechanisms. Antiviral Therapy 2004;9(6):849-863.
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Windsor L, Morahan G, Huang D, McCann V, Jones T, James I, Christiansen F, Price P. Alleles of the IL2B3’UTR associate with late onset type diabetes. Human Immunology 2004;65(12):1432-1436.
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Keane NM, Price P, Lee S, Almeida CA, Stone SF, James IR, French, MA. Restoration of CD4 T-cell responses to cytomegalovirus is short lived in severely immunodeficient HIV patients responding to HAART. HIV Medicine 2004;5(6):407-414.
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McLure CA, Dawkins RL, Williamson JF, Davies RA, Berry J, Laird NL, Gaudieri S. Amino Acid Patterns Within Short Consensus Repeats Define Conserved Duplicons Shared by Genes of the RCA Complex. J Mol Evol 2004;59(2):143-157.
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Price P, James I, Fernandez S, French MA. Alleles of the gene encoding IL-1alpha may predict control of plasma viraemia in HIV-1 patients on highly active antiretroviral therapy. AIDS 2004;18(11):1495-1501.
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Martin A, Smith D, Carr A, Hoy J, Chuah J, Mallal S, Law M, Clements M, Cooper DA. Progression of Lipodystrophy (LD) with Continued Thymidine Analogue Usage: Long-Term Follow-Up from a Randomized Clinical Trial (The PIILR Study). HIV Clin Trials 2004;5(4):192-200.
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Allen TM, Altfeld M, Yu XG, O'Sullivan KM, Lichterfeld M, Le Gall S, John M, Mothe BR, Lee PK, Kalife ET, Cohen DE, Freedberg KA, Strick DA, Johnston MN, Sette A, Rosenberg ES, Mallal SA, Goulder PJ, Brander C, Walker BD. Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection. Journal of Virology 2004;78(13):7069-78.
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Martin AM, Kulski JK, Gaudieri S, Witt CS, Freitas EM, Trowsdale J, Christiansen FT. Comparative genomic analysis, diversity and evolution of two common KIR haplotypes A and B. Gene 2004;335:121-131.
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Hammond E, Nolan D, James I, Metcalf C, Mallal S. Reduction of mitochondrial DNA content and respiratory chain activity occurs in adipocytes within 6- 12 months of commencing nucleoside reverse transcriptase inhibitor therapy. AIDS 2004;18(5):815-817.
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Martin AM, Nolan D, Gaudieri S, Almeida CA, Nolan R, James I, Carvalho F, Phillips E, Christiansen FT, Purcell AW, McCluskey J, Mallal S. Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proceedings of the National Academy of Science 2004;101(12):4180-4185.
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Nolan D, Martin A, Mallal S. Genetic susceptibility to abacavir hypersensitivity syndrome. Contagion 2004;1(1):40-44.
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Nolan D, Pace C. Potential roles for uncoupling proteins in HIV lipodystrophy. Mitochondrion 2004;4:185-191.
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Christiansen F, John M, James I, Witt C, Mallal S. Immune escape mutations in HIV-1 sequence: the influence of HLA class I and II alleles in a host population on viral evolution. Human Immunology 2003;63(10 Suppl):35.
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Nolan D, Hammond E, James I, McKinnon E, Mallal, S. Contribution of nucleoside-analogue reverse-transcriptase inhibitor therapy to lipoatrophy from the population level to the cellular level. Antiviral Therapy 2003;8(6):617-626.
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Nolan D, Watts GF, Herrmann SE, French MA, John M, Mallal, S. Endothelial function in HIV-infected patients receiving protease inhibitor therapy: does immune competence affect cardiovascular risk. Quarterly Journal of Medicine 2003;96(11):825-832.
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Pace CS, Martin AM, Hammond EL, Mamotte CD, Nolan DA, Mallal SA. Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients. Antivir Ther. 2003;8(4):323-331.
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Miller J, Carr A, Emery S, Law M, Mallal S, Baker D, Smith D, Kaldor J, Cooper DA. HIV lipodystrophy: prevalence, severity and correlates of risk in Australia. HIV Medicine 2003;4(3):293-301.
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Nolan D, Hammond E, Martin A, Taylor L, Herrmann S, McKinnon E, Metcalf C, Latham B, Mallal, S. Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS 2003;17(9):1329-1338.
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Martin A, Hammond E, Nolan D, Pace C, Den Boer M, Taylor L, Moore H, Martinez OP, Christiansen F, Mallal S. Accumulation of mitochondrial DNA mutations in human immunodeficiency virus-infected patients treated with nucleoside analogue- reverse transcriptase inhibitors. American Journal of Human Genetics 2003;72 (3 ):549-560.
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John M, McKinnon EJ, James IR, Nolan DA, Herrmann SE, Moore CB, White AJ, Mallal SA. Randomized, controlled, 48-week study of switching stavudine and/or protease inhibitors to combivir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients. Journal of Acquired Immune Deficiency Syndrome 2003;33(1):29-33.
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Nolan D, Moore C, Castley A, Sayer D, Mamotte C, John M, James I, Mallal S. Tumour necrosis factor-alpha gene -238G/A promoter polymorphism associated with a more rapid onset of lipodystrophy. AIDS 2003;17(1):121-123.
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Hammond EL, Sayer D, Nolan D, Walker U, deRonde A, Montaner J, Cote H, Gahan M, Cherry CL, Wesselingh S, Reiss P, Mallal S. Assessment of precision and concordance of quantitative mitochondrial DNA assays: a collaborative international quality assurance study. Journal of Clinical Virology 2003;27(1):97-110.
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Christiansen FT, Moore CB, De Santis D, Gaudieri S, Witt CS, James IR, Mallal SA. HLA and NK receptor genes in HIV progression. Genes and Immunity 2003;4(24, Suppl. 1):6.
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McKinnon EJ, James IR, John M, Mallal, SA. Viral load detectability profiles for HIV-infection. Statistics in Medicine 2003;22(3):385-396.
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Telenti A, Beckmann J, Mallal S. HLA and HIV: modeling adaptation to moving targets. Pharmacogenomics J 2003;3(5):254-256.
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Harvey ML, Dadour IR, Gaudieri, S. Mitochondrial DNA oxidase I gene useful in distinction between immature stages of some forensically important fly species (Diptera) in south-west Western Australia. Forensic International 2003;131(2-3):134-139.
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Moore CB, John M, James IR, Christiansen FT, Witt CS, Mallal SA. Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level. Science 2002;296(5572):1439-1443.
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Mallal S, Nolan D, Witt C, Masel G, Martin AM, Moore C, Sayer D, Castley A, Mamotte C, Maxwell D, James I, Christiansen FT. Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet 2002;359(9308):727-732.
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Martin AM, Kulski J, Witt C, Pontarotti P, Christiansen FT. Leucocyte Ig-receptor complex (LRC) in mice and men. Trends in Immunology 2002;23(2):81-88.
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Hammond EL, Lymbery A, Martin GB, Groth D, Wetherall, JD. Microsatellite analysis of genetic diversity in the emu. Journal of Heredity 2002;93(5):376-380.
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Doherty DA, James IR, Newnham, JP. Estimation of the Doppler ultrasound maximal umbilical waveform envelope: I. Estimation method. Ultrasound in Medicine & Biology 2002;28(10):1251-1259.
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Doherty DA, James IR, Newnham JP . Estimation of Doppler ultrasound maximal umbilical waveform envelope: II. Prediction of fetal distress. Ultrasound in Medicine & Biology 2002;28(10):1261-1270.
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Witt CS, Whiteway JM, Warren HS, Barden A, Rogers M, Martin A, Beilin L, Christiansen F. Alleles of the KIR2DL4 receptor and their lack of association with pre-eclampsia. European Journal of Immunology 2002;32(1):18-29.
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Carr A, Chuah J, Hudson J, Mallal SA, Law M, Hoy J, Doong N, French MAH, Smith D, Cooper DA. HIV protease inhibitor substitution in patients with lipodystrophy: a randomised, controlled, open-label, multicenter study. AIDS 2001;15(14):1811-1822.
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Nolan D, Upton R, McKinnon E, John M, James I, Adler B, Roff G, Vasikaran S, Mallal SA. Stable or increasing bone mineral density in HIV-infected patients treated with nelfinavir or indinavir. AIDS 2001;15(10):1275-1280.
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John M, Moore CB, James IR, Nolan D, Upton RP, McKinnon EJ, Mallal SA. Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy. AIDS 2001;15(6):717-723.
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Nolan D, Mallal SA. Effects of sex and race on lipodystrophy pathogenesis. Journal of HIV Therapy 2001;6(2):32-36.
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Rooney P, Taylor S, Couldwell D, Austin D, Block M, Quant D, Gowers A, O'Conor C, Gorton C, Allen D, Mulhall B, Mutimer K, Smith D, Keeffe N, Cooper D, Carr A, Miller J, Finlayson R, Wheatley D, Ellis D, Baker D, Kidd J, McFarlane R, Liang MT, Brown K, Petoumenos K, Law M, Smith D, Huffman S, Savage J, Morgan S, Knibbs P, Sowden D, Rawlinson M, Walker A, Orth D, Lister G, Chuah J, Fankhauser W, Dickson B, Bradford D, Wilson C, Ree H, Magon H, Fairley CK, Roth N, Eu B, Strecker S, Russell D, McGovern G, McNair R, Bal J, Daye J, Mallal S, French M, Skett J, Moore C, Maxwell D, Cain A, Medland N. Time trends in antiretroviral treatment use in Australia. Venereology - The Interdisciplinary International Journal of Sexual Health 2001;14(4):162-168.
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Murray R, Mallal SA, Heath C, French MAH. Cerebral mycobacterium avium infection in an HIV-infected patient following immune reconstitution and cessation of therapy for disseminated mycobacterium avium complex infection. European Journal of Clinical Microbiology and Infectious Diseases 2001;20(3):199-201.
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Ioannidis JPA, Rosenberg RS, Goedert JJ, Ashton LJ, Benfield TL, Buchbinder SP, Coutinho RA, Eugen-Olsen J, Gallart T, Katzenstein TL, Kostrikis LG, Kuipers H, Louie L, Mallal SA, Margolick JB, Martinez OP, Meyer L, Michael NL, Operskalski E, Pantaleo G, Rizzardi GP, Schuitemaker H, Haynes W, Sheppard HW, Stewart GJ, Theodorou ID, Ullum H, Vicenzi E, Vlahov D, Wilkinson D, Workman C, Zagury JF, O’Brien TR. Effects of CCR5-32, CCR2 64I and SDF-1 3’A polymorphisms on HIV disease progression: An international meta-analysis of individual-patient data. Annals of Internal Medicine 2001;135(9):782-795.
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Nolan D, Upton R, McKinnon E, John M, James I, Adler B, Roff G, Vasikaran S, Mallal SA. Stable or increasing bone mineral density in HIV-infected patients treated with Nelfinavir or Indinavir. AIDS 2001;15(10):1275-1280.
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de Meijer RJ, James I, Jennings P, Koeyers J. Cluster analysis of radionuclide concentrations in beach sand. Applied Radiation and Isotopes 2001;54(3):535-542.
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Vu HTV, Segal MR, Knuiman MW, James IR. Asymptotic and small sample statistical properties of random frailty variance estimates for shared gamma frailty models. Communications in Statistics- Simulation- and Computation 2001;30(3):581-595.
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Keane NM, Price P, Stone SF, John M, Murray RJ, French MA. Assessment of immune function by lymphoproliferation underestimates lymphocyte functional capacity in HIV patients treated with highly active antiretroviral therapy. AIDS Res Hum Retroviruses 2000;16(18):1991-1996.
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Witt CS, Martin A, Christiansen FT. Detection of KIR2DL4 alleles by sequencing and SSCP reveals a common allele with a shortened cytoplasmic tail. Tissue Antigens 2000;56(3):248-257.
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Mallal SA, John M, Moore CB, James IR, McKinnon EJ. Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection. AIDS 2000;14(10):1309-1316.
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Gillieatt SJ, Mallal S. Uptake of HIV testing and treatment in an isolated population with access to free and universal health care. International Journal of STD & AIDS 2000;11(5):303-312.
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Martin AM, Freitas EM, Witt CS, Christiansen FT . The genomic organization and evolution of the natural killer immunoglobulin-like receptor (KIR) gene cluster . Immunogenetics 2000;51(4-5):268-280.
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French MAH, Lenzo N, John M, Mallal SA, McKinnon EJ, James I, Price P, Flexman J, Tay-Kearney ML. Immune restoration disease after the treatment of immunodeficient HIV-infected patients with highly active anti-retroviral therapy. HIV Medicine 2000;1(2):107-115.
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Nolan D, Upton R, James I, McKinnon E, John M, Mallal S. Longitudinal analysis of bone mineral density (BMD) in HIV-infected patients treated with HAART: Changes in BMD correlate with change in subcutaneous fat; with an additional independent effect of indinavir therapy to increase BMD. Antiviral Therapy 2000;5(Suppl):20.
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John M, Lam M, Latham B, Saker B, French M. Nephrotic syndrome in a patient with IgA deficiency-associated mesangioproliferative glomerulonephritis. Pathology 2000;32:56-58.
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Allcock RJN, Martin AM, Price P. The mouse as a model for the effects of MHC genes on human disease. Immunology Today 2000;328(21):328-333.
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Kulski, JK, S Gaudieri, A Martin, RL Dawkins. Co-evolution of PERB-11 (MIC) and HLA ClassI genes with HERV-16 and retroelements by extended genomic duplications. J. Mol. Evol 1999;49 (1):84-97.
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